How

STRmix™ combines sophisticated biological modelling and standard mathematical processes to interpret a wide range of complex DNA profiles.  

Using well-established statistical methods, the software builds millions of conceptual DNA profiles.  It grades them against the evidential sample, finding the combinations that best explain the profile.  A range of Likelihood Ratio options are provided for subsequent comparisons to reference profiles. 

Using a Markov Chain Monte Carlo engine, STRmix™ models any types of allelic and stutter peak heights as well as drop-in and drop out behaviour.  It does this rapidly, accessing evidential information previously out of reach with traditional methods.   

STRmix™ is supported by comprehensive empirical studies with its mathematics readily accessible to DNA analysts, so results are easily explained in court. 

Validation 

STRmix™ has been extensively validated and is in use for casework interpretation at PHF Science (formerly ESR) and multiple Australian, US, European, Canadian, Asian and UK laboratories (first implemented in August 2012).  STRmix™ has achieved Certificate of Networthiness (CoN) status on the United States Army Network.